Integrin alpha 2b Ab

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Integrin alpha 2b Ab
Immunohistochemical analysis of paraffin-embedded Human placenta, using the Antibody at 1:100 dilution.
Integrin alpha 2b Ab
Immunohistochemical analysis of paraffin-embedded Rat pancreas, using the Antibody at 1:100 dilution.
Integrin alpha 2b Ab
Immunohistochemical analysis of paraffin-embedded Human squamous carcinoma, using the Antibody at 1:100 dilution.
Integrin alpha 2b Ab
Immunohistochemical analysis of paraffin-embedded Human placenta, using the Antibody at 1:100 dilution.
Integrin alpha 2b Ab
Immunohistochemical analysis of paraffin-embedded Rat pancreas, using the Antibody at 1:100 dilution.

产品简介

Product Introduction

Catalog No.

CY6790

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human

Application

WB;IHC

Calculated Mol Weight

113 kDa

Observed Mol Weight

135 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

Alternative Names

Integrin alpha-Iib; GPalpha Iib; GPIIb; Platelet membrane glycoprotein Iib; CD41; ITGA2B; GP2B; ITGAB;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Purification

Affinity-chromatography

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

引用文献

Citation

期刊名称:

ARCHIVES OF DERMATOLOGICAL RESEARCH

PMID:

39673600

影响因子:

1.8

应用范围:

IHC

检测物种:

Human

发表时间:

2024-12-14

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CY6790

Specifications:

50μl, 150μl

Price:

$188/50μl, $368/150μl

Delivery time:

1-4 weeks

Ordering information:

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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