ERK2 Ab - Abways

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ERK2 Ab

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Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:6K dilution)

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Immunohistochemical analysis of paraffin-embedded Rat lung, using the Antibody at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded Rat skin, using the Antibody at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded Human melanoma, using the Antibody at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded Human renal cancer, using the Antibody at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded Mouse ovary, using the Antibody at 1:100 dilution.

Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma, using ERK2 Antibody.

Immunofluorescent analysis using the Antibody at 1:50 dilution.

Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:6K dilution)

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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产品简介

Product Introduction

Catalog No.

CY5045

Source

Recombinant Rabbit mAb

UniProt ID

P28482

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

41 kDa

Observed Mol Weight

41 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

ERK2; PRKM1; PRKM2; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; ERT1; Extracellular signal-regulated kinase 2 (ERK-2); MAP kinase isoform p42 (p42-MAPK); Mitogen-activated protein kinase 2 (MAP kinase 2; MAPK 2); MAPK1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ERK2

Purification

Affinity-chromatography

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

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