ABI2 Ab
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ABI2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ABI2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ABI2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ABI2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ABI2 Ab
ABI2 Ab
ABI2 Ab
ABI2 Ab
ABI2 Ab
ABI2 Ab
ABI2 Ab
ABI2 Ab

产品简介

Product Introduction

Catalog No.

BY2230

Source

Rabbit pAb

UniProt ID

Q9NYB9

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IP;FC

Calculated Mol Weight

56 kDa

Observed Mol Weight

75 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Abelson interactor 2; ABI2; ABI2B; Abl binding protein 3; AblBP3; ArgBP1; ARGBPIA; ArgBPIB; SSH3BP2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ABI2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation.Acts as a regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge.

引用文献

Citation

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BY2230

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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