TGFBI Antibody
Source: Monoclonal Antibodies Catalog No. : CY1115
TGFBI Antibody (CY1115)
UniProt:Q15582
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References(1)
http://www.abways.com/showproduct.asp?cid=CY1115
Data Sheet
-
UniProt
-
Mol Weight68kDa
-
Alternative NamesBeta ig; Beta ig h3; Beta ig-h3; BGH3_HUMAN; Big h3; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; Kerato epithelin; Kerato-epithelin; LCD1;
-
ImmunogenA synthesized peptide derived from human TGFBI
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionTGFBI is a RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC,ICC/IF
-
Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
-
Western blot analysis of TGFBI expression in Human fetal kidney lysate.
-
Immunohistochemical analysis of paraffin-embedded human kideny, using TGFBI Antibody.
-
Immunofluorescent analysis of MCF-7 cells, using TGFBI Antibody .
-
Overexpression of the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis. -Cellular Signalling
-
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
-
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
References (1)
Overexpression of the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis.-Cellular Signalling